GFRA-4-His, human recombinant
P-123-100
Datasheet as| Name | GFRA-4, human recombinant |
| Synonyms | Persephin receptor |
| Uniprot ID | Q9GZZ7 |
| Source | Human |
| MW | Approximately 25.1 kDa, a single non-glycosylated polypeptide chain containing 233 amino acids including C-terminal hexahistidine tag |
| Host | CHO-based cell line (expressed by QMCF Technology) |
| Purification | Purified by Ni-affinity chromatography and gel-filtration from serum-free CHO growth media |
| Concentration | 1.3 mg/ml |
| Buffer | PBS pH 7.4 |
| Endotoxine | Not tested |
| QC | Coomassie-stained SDS-PAGE 12%, 2 µg per lane |
| Background | Receptor
for persephin. Mediates the GDNF- induced autophosphorylation and activation of
the RET receptor. May be important in C-cell development and, in the postnatal
development of the adrenal medulla |
| Shipping | Shipped on dry ice |
| Storage | Store at -70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
Figure 1. SDS-PAGE analysis of human GFRA-4 visualized by PageBlue protein staining solution (Fermentas). Lane 1. 2 µg of human GFRA-4 (reduced); Lane 2. Protein size marker ( Prestained protein ladder, 8003, Naxo); Lane 3. 2 µg of human GFRA-4 (non-reduced)