Proteins

GFRA-2-His, human recombinant

P-121-100

Name GFRA-2, human recombinant
Synonyms RET ligand 2,TGF-beta-related neurotrophic factor receptor 2
Uniprot ID O00451
Source Human
MW Approximately 47.9 kDa, a single non-glycosylated polypeptide chain containing 428 amino acids including C-terminal hexahistidine tag
Host CHO-based cell line (expressed by QMCF Technology)
Purification Purified by Ni-affinity chromatography and gel-filtration from serum-free CHO growth media
Concentration 0.7 mg/ml
Buffer PBS pH 7.4
Endotoxine Not tested
QC Coomassie-stained SDS-PAGE 12%, 2 µg per lane
Background Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor
Shipping Shipped on dry ice
Storage Store at -70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
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Figure 1. SDS-PAGE analysis of human GFRA-2 visualized by PageBlue protein staining solution (Fermentas). Lane 1. 2 µg of human GFRA-2 (reduced); Lane 2. Protein size marker ( Prestained protein ladder, 8003, Naxo); Lane 3. 2 µg of human GFRA-2 (non-reduced)