2B4-His, mouse recombinant
P-405-100
| Name | 2B4, mouse recombinant |
| Description | Protein contains only extracellular domain of the human 2B4 (aa 20-225) |
| Synonyms | NK
cell type I receptor protein 2B4, SLAM family member 4, Signaling lymphocytic
activation molecule 4, CD antigen: CD244 |
| Uniprot ID | Q07763 |
| Source |
Mouse |
| MW | Approximately 17.8 kDa, a single non-glycosylated polypeptide chain containing 219 amino acids including C-terminal hexahistidine tag |
| Host | CHO-based cell line (expressed by QMCF Technology) |
| Purification | Purified by Ni-affinity chromatography, ion-exchange chromatography and desalting chromatography from serum-free CHO growth media |
| Concentration | 0.2 mg/ml |
| Buffer | PBS pH 6.0 |
| Endotoxine | Not tested |
| QC | Coomassie-stained SDS-PAGE 15%, 2 µg per lane |
| Background | Modulate
other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4
is the only heterophilic receptor of SLAM family |
| Shipping | Shipped on dry ice |
| Storage | Store at -70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
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Figure 1. SDS-PAGE analysis of mouse 2B4 visualized by PageBlue protein staining solution (Fermentas). Lane 1. 2 µg of mouse 2B4 (reduced); Lane 2. Protein size marker ( Prestained protein ladder, 8003, Naxo); Lane 3. 2 µg of mouse 2B4 (non-reduced)