Monoclonal antibody to Human Cardiac Troponin I
R1-126-100
Datasheet as| Name | Monoclonal antibody to Human Cardiac Troponin I, clone 5F8 |
| Immunogen | Recombinant human cardiac troponin complex |
| Immunogen Description | Recombinant human cardiac troponin complex protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line |
| Clonality | Recombinant human monoclonal |
| Clone | 5F8 |
| Class | Human IgG2-lambda |
| Reactivity | human cardiac troponin I |
| Dissociation constant (KD) | 1.60 x e-10 M (Troponin complex binding from solution)
1 x e-12 M (Troponin complex binding from streptavidin surface) |
| Application | ELISA |
| Purification | MabSelect affinity chromatography following gel filtration |
| Buffer | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 (SPTN) |
| Unit Size | 100 µg |
| Related Products |
Monoclonal antibodies to human cardiac troponin I. For more information visitwww.icosagen.com/antibodies
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| Shipping |
This product is shipped in non-frozen liquid form in ambient conditions
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| Storage |
Store at –20…-70°C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles
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| Background |
Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle (Wikipedia)
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| Limitations | This product is for research use only. |
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Price per quantity:
€308 / 100µg
€1231 / 500µg
€1999 / 1000µg