Mouse monoclonal antibody to human laminin a5
A2-610-100
Datasheet as| Name | Mouse monoclonal antibody to human laminin a5 |
| Immunogen | Human laminin a5 |
| Immunogen Description | Laminin purified from human placenta (Chemicon) |
| Uniprot ID | - |
| Alternative Names | - |
| Clonality | Mouse monoclonal |
| Clone | 4B12 |
| Class | IgG1 |
| Reactivity | Human laminin α5 |
| Application | ELISA, IP, IHC |
| Protocol |
ELISA 0.05 to 0.1 µg/ml; IP 0.5 mg/ml This antibody does not work in WB Monoclonal antibody working titer has to be established practically for each particular antigen and assay format |
| Purification | Protein G purification |
| Buffer | PBS pH 7.4, with 0.1% sodium azide |
| Unit Size | 100 µg |
| Related Products | Monoclonal antibodies to human laminin. For more information visit www.icosagen.com/antibodies |
| Shipping | This product is shipped in non-frozen liquid form in ambient conditions |
| Storage | Store at -20…-70°C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles |
| Background | Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cell-surface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination,laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their α chain, are expressed in a cell- and tissue-specific manner, and are differentially recognized by integrins |
| References | Wondimu Z, Geberhiwot T, Ingerpuu S, Juronen E, Xie X, Lindbom L, Doi M, Kortesmaa J, Thyboll J, Tryggvason K, Fadeel B, Patarroyo M. (2004) An endothelial laminin isoform, laminin-8 (α4β1γ1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis. Blood, 104(6):1859-66 |
| Limitations | This product is for research use only |
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€299 / 100µg
